Table 1.
Patient Characteristics (N = 282)
| Characteristics | No. | % |
|---|---|---|
| Age, years | ||
| Median | 46.3 | |
| Range | 13-86.4 | |
| Sex | ||
| Male | 157 | 55.7 |
| Female | 125 | 44.3 |
| Sokal risk group* | ||
| Low | 88 | 31.8 |
| Intermediate | 111 | 40.1 |
| High | 78 | 28.1 |
| Interval since diagnosis, months | ||
| Median | 1.5 | |
| Range | 0-6 | |
| Chromosomal abnormalities in addition to the Philadelphia chromosome† | 16 | 6.0 |
| Splenomegaly‡ | 186 | 66.4 |
| Spleen size ≥ 10 cm below the costal margin | 75 | 26.8 |
| White cell count × 109/L | ||
| Median | 140.5 | |
| Range | 5.8-645 | |
| Platelet count × 109/L | ||
| Median | 396 | |
| Range | 108-2,267 | |
| Hemoglobin, g/L | ||
| Median | 116.0 | |
| Range | 33.0-172.0 | |
| Peripheral blood blasts (%) | ||
| Median | 1 | |
| Range | 0-14 | |
| Peripheral blood basophils (%) | ||
| Median | 2.6 | |
| Range | 0-18 | |
*
We could not calculate the Sokal score in five patients because of missing data.
†
The most common additional abnormalities were a second Philadelphia chromosome and trisomy of chromosome 8. Data were missing in 17 patients.
‡
Two patients had missing data; splenomegaly was defined as a palpable spleen in the physical examination and measured in centimeters below the costal margin.