Table 3.
RRs for 8-Year OS and c-CCyRS According to the Cytogenetic and Molecular Responses Achieved at 6 or 12 Months
| Variable | No. of Patients | 8-Year OS |
8-Year c-CCyRS |
||
|---|---|---|---|---|---|
| RR | P | RR | P | ||
| 6 months | |||||
| CCyR* | .29 | .12 | |||
| Yes | 106 | 1 | 1 | ||
| No | 157 | 3.44 | 0.815 | ||
| MCyR* | .033 | .01 | |||
| Yes | 170 | 1 | 1 | ||
| No | 93 | 2.30 | 0.715 | ||
| MiCyR* | .29 | .23 | |||
| Yes | 223 | 1 | 1 | ||
| No | 40 | 2.15 | 0.727 | ||
| BCR-ABL1/ABL1 | < .001 | < .001 | |||
| Good response (≤ 1.67%) | 87 | 1 | 1 | ||
| Poor response (≥ 1.67%) | 187 | 4.83 | 0.486 | ||
| 12 months | |||||
| CCyR† | .016 | .003 | |||
| Yes | 164 | 1 | 1 | ||
| No | 89 | 2.88 | 0.674 | ||
| MCyR† | .08 | .007 | |||
| Yes | 199 | 1 | 1 | ||
| No | 54 | 2.40 | 0.714 | ||
| BCR-ABL1/ABL1 | < .001 | < .001 | |||
| Good response (≤0.53%) | 164 | 1 | 1 | ||
| Poor response (≥0.53%) | 93 | 6.33 | 0.545 | ||
Abbreviations: c-CCyRS, current complete cytogenetic response survival; CCyR, complete cytogenetic response; MCyR, major cytogenetic response; MiCyR, minor cytogenetic response; OS, overall survival; RR, relative risk.
*
Data missing in 11 patients
†
Data missing in four patients.