Table A1.
RR for OS, PFS, EFS and Cumulative Incidence of CCyR, MMR, and CMR, and c-CCyRS at 8 Years According to the Pretherapy Characteristics of the Patients
| Variable | OS |
PFS |
EFS |
CCyR |
MMR |
CMR |
c-CCyRS |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RR | P | RR | P | RR | P | RR | P | RR | P | RR | P | RR | P | |
| Age (years) | 1.021 | .14 | 1.017 | .14 | 1.006 | .36 | 0.990 | .74 | 1.002 | .75 | 1.013 | .23 | 0.998 | .64 |
| Sex (female) | 0.983 | .96 | 0.963 | .91 | 1.000 | .96 | 1.142 | .31 | 1.719 | .04 | 6.491 | < .001 | 1.007 | .953 |
| Sokal risk group | .002 | .003 | .27 | < .001 | .02 | .09 | < .001 | |||||||
| Low | 1 | 1 | 1 | 1 | 1 | 1 | 1 | |||||||
| Intermediate | 2.279 | 1.646 | 1.260 | 0.800 | 0.814 | 0.570 | 0.786 | |||||||
| High | 5.532 | 3.944 | 1.388 | 0.506 | 0.622 | 0.492 | 0.498 | |||||||
| CE | 1.655 | .5 | 2.180 | .21 | 0.761 | .52 | 1.171 | .51 | 1.411 | .29 | 1.101 | .47 | 1.096 | .75 |
| Splenomegaly (cm) | 1.056 | .03 | 1.045 | .06 | 1.029 | .007 | 0.958 | < .001 | 0.938 | < .001 | 0.847 | < .001 | 0.935 | < .001 |
| White cell count (×109/L) | 1.003 | .01 | 1.002 | .05 | 1.002 | < .001 | 0.997 | < .001 | 0.996 | < .001 | 0.989 | < .001 | 0.998 | .01 |
| Platelet count (×109/L) | 1.000 | .91 | 1.000 | .57 | 1.001 | .006 | 1.001 | .005 | 1.001 | .03 | 1.001 | .001 | 1.000 | .64 |
| Hemoglobin (g/dL) | 0.733 | .001 | 0.790 | .005 | 0.878 | .01 | 1.207 | < .001 | 1.221 | < .001 | 1.258 | .02 | 1.116 | .001 |
| Peripheral blood blasts (%) | 1.082 | .07 | 1.094 | .06 | 1.121 | .001 | 0.928 | .005 | 0.953 | .12 | 0.648 | .01 | 0.964 | .11 |
| Peripheral blood basophils (%) | 1.058 | .25 | 1.033 | .51 | 0.974 | .31 | 1.023 | .18 | 1.030 | .13 | 1.027 | .19 | 1.017 | .34 |
Abbreviations: c-CCyRS, current complete cytogenetic response survival; CCyR, complete cytogenetic response; CMR, complete molecular response; CE, chromosomal abnormalities in addition to the Philadelphia chromosome; EFS, event-free survival; MMR, major molecular response; OS, overall survival; PFS, progression-free survival; RR, relative risk.