Table 4. Relative expression levels of senescence-associated mRNA in each group of BMSCs ().
n | TERT | TCAB1 | P21 | SIRT1 | SIRT6 | |
---|---|---|---|---|---|---|
Young cell group | 3 | 1.00 ± 0.04 | 1.01 ± 0.02 | 1.03 ± 0.03 | 1.00 ± 0.04 | 1.00 ± 0.09 |
Aged cell group | 3 | 0.70 ± 0.03** | 0.18 ± 0.01* | 3.45 ± 0.48** | 0.82 ± 0.02** | 0.17 ± 0.02** |
Induced aged group | 3 | 0.05 ± 0.00**△△ | 0.35 ± 0.22 | 2.31 ± 0.09** | 0.78 ± 0.12 | 0.43 ± 0.07**△△ |
Note: *Compared with the young cell group, P < 0.05, **compared with the young cell group, P < 0.01, △compared with the aged cell group, P < 0.05, and △△compared with the aged cell group, P < 0.01.