Table 2. EC50 values of EF24 against non-senescent cells (NCs), and IR- or Rep-induced senescent WI‐38 and IMR-90 fibroblasts, HUVEC, HREC and pre-adipocytes.
Cell type | EC50 (μM) | EC50 value ratio | ||||
NCs | IR-SCs | Rep-SCs | NCs/IR-SCs | NCs/Rep-SCs | ||
WI-38 | 4.32 | 1.74 | 1.26 | 2.48 | 3.43 | |
IMR-90 | 10.88 | 1.72 | 0.33 | 6.33 | 32.97 | |
HUVEC | 1.39 | 2.09 | 0.77 | 0.67 | 1.80 | |
HREC | 3.25 | 1.15 | 0.60 | 2.83 | 5.37 | |
Pre-adipocyte | 8.92 | 5.04 | 4.60 | 1.77 | 1.94 |