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. 2019 Jan 28;11(2):771–782. doi: 10.18632/aging.101787

Table 2. EC50 values of EF24 against non-senescent cells (NCs), and IR- or Rep-induced senescent WI‐38 and IMR-90 fibroblasts, HUVEC, HREC and pre-adipocytes.

Cell type EC50 (μM) EC50 value ratio
NCs IR-SCs Rep-SCs NCs/IR-SCs NCs/Rep-SCs
WI-38 4.32 1.74 1.26 2.48 3.43
IMR-90 10.88 1.72 0.33 6.33 32.97
HUVEC 1.39 2.09 0.77 0.67 1.80
HREC 3.25 1.15 0.60 2.83 5.37
Pre-adipocyte 8.92 5.04 4.60 1.77 1.94