Table 2. Overview of the cohorts used in the validation analysis.
| Smoking status | ||||||||
| Study | N | Female | Age | Never | Former | Current | Pack-years |
Years of Follow-up |
| FHS* test |
625 | 53% | 66.9±8.64 [61,73] | 37% | 52% | 10% | 14.7±19.91 [0,23] | 7.7±1.78 [7.3,8.8] |
| WHI BA23 | 2107 | 100% | 65.3±7.1 [60,70.9] | 52% | 36% | 10% | 9.5±18.55 [0,12.5] | 16.9±4.63 [15.8,19.9] |
| WHI EMPC | 1972 | 100% | 63.3±7.03 [57.9,68.7] | 52% | 38% | 9% | 9±17.27 [0,12.5] | 18±4.02 [17.9,20.1] |
| JHS | 1747 | 63% | 56.2±12.31 [46.5,65.4] | 65% | 21% | 14% | NA | 11.7±2.55 [11.2,13.1] |
| InChianti** | 924 (484) |
54% | 67±16.64 [60,78] | 57% | 29% | 14% | 10.3±17.33 [0,16.8] | 5.4±4.84 [0.1,9.3] |
NA=not available.
Quantitative variables are presented in the format of mean ±SD [25th, 75th].
*The distribution of age is based on exam 8.
**The statistics are based on the number of 924 observations across 484 individuals.
The table summarizes the characteristics of 6,935 individuals (corresponding to 7,375 Illumina arrays) from five independent cohorts that were used in our validation analysis. For example, up to two longitudinal measurements were available for each of 484 individuals in the InChianti cohort.