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. 2019 Jan 17;11(2):401–422. doi: 10.18632/aging.101748

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Copyright: © 2018 Sasaki et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Effect of oral administration of 3,4,5-tricaffeoylquinic acid (TCQA) on subventricular zone (SVZ) proliferation. SAMP8 mice were administrated with TCQA (5 mg/kg) for 30 days (A) Photomicrograph shows adult mouse brain coronal sections containing the SVZ processed for immunohistochemical detection of proliferating BrdU⁺ cells (red) and GFAP+ (green), an astrocyte marker found in SVZ NSC. (B, C) Graphs represent the number of BrdU+/GFAP+ and BrdU⁺ cells, respectively in the different treatment groups.