Extended data table 3.
Allelic complexity of the constitutive Rosa26- and H11-Cas9 families.
| Number of distinct NHEJ alleles in ‘n’ Tyrchinchilla+ offspring |
|
|---|---|
| Rosa26 Family 1 | 2 (n=9) |
| Rosa26 Family 2 | 3 (n=10) |
| Rosa26 family 3* | 2 (n=9) |
| Rosa26 Family 4 | 2 (n=9) |
| Rosa26 Family 5 | 3 (n=13) |
| H11 Family 1 | 4 (n=10) |
| H11 Family 2 | 6 (n=9) |
| H11 Family 3 | 4 (n=6) |
| H11 Family 4 | 2 (n=8) |
| H11 Family 5 | 7 (n=9) |
*
indicates a family with offspring that were Tyrchinchilla negative and mCherry negative, suggesting a large deletion in the recipient chromosome may encompass the Tyrchinchilla SNP. This was counted as one of the two unique NHEJ indels.