Table 2.
Reverters vs. Consistently Normal |
Stable MCI vs. Consistently Normal |
Progressor vs. Consistently Normal |
|||||||
---|---|---|---|---|---|---|---|---|---|
RRR | SE | p-value | RRR | SE | p-value | RRR | SE | p-value | |
>0 Subjective cognitive concerns | 22.58 | 7.46 | <0.001 | 16.33 | 4.02 | <0.001 | 12.79 | 5.64 | <0.001 |
Number of subjective concerns | 2.52 | 0.13 | <0.001 | 2.73 | 0.14 | <0.001 | 3.02 | 0.19 | <0.001 |
Self-rated health – good/very good/excellent (ref: poor/fair) |
0.417 | 0.77 | <0.001 | 0.364 | 0.064 | <0.001 | 0.424 | 0.128 | 0.004 |
>0 IADL impairments | 2.629 | 0.540 | <0.001 | 4.174 | 0.732 | <0.001 | 6.150 | 1.656 | <0.001 |
≥ 3 depressive symptoms | 2.872 | 0.728 | <0.001 | 2.557 | 0.627 | <0.001 | 3.55 | 1.283 | <0.001 |
APOE *4 genotype | 1.221 | 0.226 | 0.28 | 1.535 | 0.263 | 0.012 | 3.062 | 0.833 | <0.001 |
Systolic blood pressure (SBP) | 0.844 | 0.122 | 0.242 | 0.925 | 0.123 | 0.558 | 0.976 | 0.231 | 0.919 |
Diastolic blood pressure (DBP) | 0.993 | 0.15 | 0.96 | 0.74 | 0.1 | 0.026 | 0.757 | 0.181 | 0.245 |
Reported Stroke/TIA | 1.518 | 0.347 | 0.068 | 2.556 | 0.502 | <0.001 | 1.967 | 0.671 | 0.047 |
Reported Heart attack | 1.088 | 0.163 | 0.573 | 0.924 | 0.128 | 0.568 | 0.826 | 0.204 | 0.438 |
Reported Diabetes | 1.002 | 0.18 | 0.99 | 1.605 | 0.25 | 0.002 | 1.312 | 0.369 | 0.334 |
Smoking | 0.846 | 0.244 | 0.561 | 0.615 | 0.199 | 0.133 | 1.575 | 0.731 | 0.327 |
Alcohol | 0.543 | 0.105 | 0.002 | 0.362 | 0.06 | <0.001 | 0.306 | 0.082 | <0.001 |
Number of Prescription medications | 1.13 | 0.03 | <0.001 | 1.15 | 0.02 | <0.001 | 1.02 | 0.04 | 0.656 |
Exercise (any) | 0.807 | 0.119 | 0.146 | 0.884 | 0.12 | 0.366 | 0.676 | 0.161 | 0.1 |