Table 3.
Details of experimental and injection parameters for each procedure
| Canine | sUPE % Gd by weight (%) | sUPE injection concentration (mg/mL) | sUPE‐only injection administered? | sUPE + Optison injection administered? | Sham (saline) injection administered? |
|---|---|---|---|---|---|
| 1 | 5.4 | 1.2 | Yes | No | Yes |
| 2 | 5.4 | 1.5 | Yes | Yes | Yes |
| 4 | 5.4 | 1.2 | Yes | Yes | Yes |
| 5 | 5.0 | 1.6 | Yes | Yes | Yes |
| 6 | 4.0 | 2.0 | Yes | Yes | Yes |
All injections were 1 mL in volume. sUPE with Optison and sUPE‐only injections had the same sUPE concentration when both were administered. Canine 1 was administered only saline and sUPE‐only injections. Canine 3 was excluded from all analysis, as it was only administered one injection with a notably higher Gd2O3 concentration than the other subjects.