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. Author manuscript; available in PMC: 2019 Jul 14.
Published in final edited form as: Nat Med. 2019 Jan 14;25(2):270–276. doi: 10.1038/s41591-018-0297-y

Extended Data Figure 10. CSF sPDGFRβ and medial temporal BBB permeability Ktrans values are not correlated with age, indicating that changes in CSF sPDGFRβ and Ktrans capture processes relating to cognitive impairment independent of normal aging. In CDR 0 individuals, age does not correlate with CSF sPDGFRβ.

Extended Data Figure 10.

(a) or regional Ktrans in the hippocampus (HC) (c) and parahippocampal gyrus (PHC) (e). Similarly, in CDR 0.5 individuals, age does not correlate with CSF sPDGFRβ (a) or regional Ktrans in the hippocampus (HC) (c) and parahippocampal gyrus (PHC) (e). Statistical significance determined by Pearson correlation; r = Pearson correlation coefficient. Brackets denote sample size (n) in each analysis. Supports Figures 1 and 3.