Table 3.
Group differences in BOLD signal activation.
| Region | Contrast | % Signal Change | P |
|---|---|---|---|
| left VS | HC > CHR | 0.088 | 0.148 |
| right VS | HC > CHR | 0.013 | 0.402 |
| vmPFC | CHR > HC | 0.030 | 0.513 |
All results presented involved testing group differences in the positive – ambiguous contrast. Abbreviations: VS – ventral striatum; vmPFC – ventromedial prefrontal cortex; CHR – clinical high-risk; HC – healthy controls. CHR youth did not exhibit significantly decreased bilateral VS response in comparison to HCs. CHR youth also did not show significantly elevated vmPFC activation relative to the HC group.