Table 5.

Relationships between regional activation and clinical symptoms.

Test	Region	β	P
Social anhedonia	left vs	0.008	0.425
Anticipatory anhedonia	left vs	0.578	0.761
Consummatory anhedonia	left vs	1.651	0.431
Social anhedonia	right vs	0.011	0.168
Anticipatory anhedonia	right vs	−0.256	0.550
Consummatory anhedonia	right vs	1.739	0.291
Social anhedonia	vmPFC	0.235	0.047
Anticipatory anhedonia	vmPFC	−2.330	0.436
Consummatory anhedonia	vmPFC	−1.097	0.542

Abbreviations: VS – ventral striatum; vmPFC – ventromedial prefrontal cortex. Positive relationships were tested involving social anhedonia, given that higher social anhedonia scores (derived from the social anhedonia scale – SAS-R) equal greater impairment. Negative relationships were tested for anticipatory and consummatory anhedonia, given that higher anticipatory and consummatory anhedonia scores (derived from the temporal experience of pleasure scale – TEPS) equal less impairment. β values refer to the parameter estimates extracted from higher-level analyses using FSL’s featquery.

Relationships were considered significant at p < 0.05 using Threshold-Free Cluster Enhancement (TFCE) in FSL’s randomise function, and corrected for multiple comparisons using FWE.