Table 6.

Relationships between task-based connectivity and clinical symptoms.

Test	Source - Target	β	P
Social anhedonia	vmPFC - left vs	0.001	0.732
Anticipatory anhedonia	vmPFC - left vs	−0.024	0.612
Consummatory anhedonia	vmPFC - left vs	−0.022	0.638
Social anhedonia	vmPFC - right vs	0.002	0.236
Anticipatory anhedonia	vmPFC - right vs	−0.059	0.040
Consummatory anhedonia	vmPFC - right vs	−0.066	0.008

Abbreviations: VS – ventral striatum; vmPFC – ventromedial prefrontal cortex. All relationships examined were based on a priori hypotheses. Tests examined positive relationships, other than those involving anticipatory and consummatory anhedonia, as higher ratings on these scales equaled less impairment and required testing negative relationships. β values refer to the parameter estimates extracted from higher-level analyses using FSL’s featquery.

Relationships were considered significant at p < 0.05 using Threshold-Free Cluster Enhancement (TFCE) in FSL’s randomise function, and corrected for multiple comparisons using FWE.