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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Rapid Commun Mass Spectrom. 2019 Jan 1;33(Suppl 1):75–85. doi: 10.1002/rcm.8258

Figure 5: Cluster analysis of percentage deuteration data after one minute of deuteration.

Figure 5:

The cluster analysis was performed with R-3.3.140, 41 under use of the euclidean algorithm. The obtained percentage deuteration levels of those peptides that showed significant (p-value < 0.001) differences for at least one ligand with respect to the obtained values for the free PPARγ were used for the analysis. This cluster analysis confirms the assumption that DEHP does not bind to the PPARγ LBD while 15Δ-PGJ2, MEHP and MEOHP do bind because DEHP clustered with the free PPARγ and MEHP and MEOHP clustered with the positive control 15Δ-PGJ2.