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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Rapid Commun Mass Spectrom. 2019 Jan 1;33(Suppl 1):75–85. doi: 10.1002/rcm.8258

Figure 7: Dose response curves for DEHP and its metabolites MEHP and MEOHP.

Figure 7:

Presented are the observed cytotoxicity (white symbols, right y-axis) and activation of PPARγ (green symbols, left y-axis) relative to the agonist rosiglitazone for DEHP (A), MEHP (B) and MEOHP (C). The activation of PPARγ is shown as full dose-response curve (left) and as linear dose-response curve (right). The EC10 of each compound was derived from the linear dose response curve. Different symbols represent three independent experiments.