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. 2018 Aug 24;58(1):109–113. doi: 10.2169/internalmedicine.0317-17

Table.

Myelodysplastic Syndrome Reported in Patients with Werner Syndrome.

Case Sex WS diagnostic confidence Age at neoplasm diagnosis Histopathologic diagnosis Treatment Clinical result Reference
1 M Possible 44 Myelodysplasia/
myelofibrosis
Etoposide Died, sepsis [16]
2 M Possible 62 Myelodysplasia Transfusion Died, interstitial pneumonitis [20]
3 M Possible 61 RAEB/
myelofibrosis
Transfusion Died, pneumonia [21]
4 M Probable 63 RAEB Transfusion Died, pneumonia [22]
5 M Possible 52 Myelodysplasia Unknown Unknown [23]
6 M Definite 29 RAEB-t Unknown Unknown [24]
7 F Probable 52 Myelodysplasia Watch & wait Unknown [25]
8 M Definite 43 RAEB-1 Azacitidine Died, pneumonia [26]
9 M Definite 44 RAEB-2 Allo-HSCT Complete remission Present case

WS: Werner syndrome, M: male, F: female, RAEB: refractory anemia with excess of blast, RAEB-t: refractory anemia with excess of blast in transformation, HSCT: hematopoietic stem cell transplantation