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. 2019 Jan 23;9(1):180238. doi: 10.1098/rsob.180238

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© 2019 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 4. — Differentially expressed genes were mainly enriched in four clusters. Cluster analysis of genes with altered expression was performed using microarray analysis, mRNA levels were analysed among control (con.), model (mod.) and recovery (rec.) groups. (a) The tissue screen identified 3716 genes whose mRNA levels changed at least twofold when comparing the data from any two groups. Green, black and red represent lower, normal and higher mRNA expression relative to that of control, respectively. The 3716 genes were classified into four clusters (clusters 1–4) using TreeView software. (b) Representative changes of dynamic gene expression curves for each cluster. Expression levels of each gene were compared with regard to the different status of rabbit atherosclerosis.