Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 1;10:39. doi: 10.3389/fphar.2019.00039

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Lichnog, Klabunde, Becker, Fuh, Tripal, Atreya, Klenske, Erickson, Chiu, Reed, Chung, Neufert, Atreya, McBride, Neurath and Zundler.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Assessment of etrolizumab-s internalization by STED microscopy. (A) Representative STED microscopy images showing localization and distribution of β7 integrin on the surface of cells from CD, UC, and CON donors. Additionally, a negative control (NEG) without primary antibody staining is shown. Images are representative for seven independent experiments. (B) Representative images showing etrolizumab-s localization on/in cells incubated with etrolizumab-s at 4°C or cells incubated with etrolizumab-s at 37°C and additionally treated with or without Triton-X. Additionally, a negative control without primary antibody staining is shown. Images are representative for five independent experiments.