Table 2.
Comparison of pain, VA, and CMT values and their changes during the study follow-up among different injection sites
| Total | Injection site | p-Valuea | ||||
|---|---|---|---|---|---|---|
| IN | IT | SN | ST | |||
| Pain | 2.9 ± 2.2 | 3 ± 2.3 | 3 ± 2.1 | 1.5 ± 1.7 | 4 ± 2 | <0.001 |
| Pre-injection BCVA (logMAR) | 0.64 ± 0.35 | 0.61 ± 0.37 | 0.65 ± 0.41 | 0.6 ± 0.31 | 0.69 ± 0.3 | 0.022 |
| Post-injection BCVA (logMAR) | 0.49 ± 0.26 | 0.42 ± 0.27 | 0.53 ± 0.24 | 0.48 ± 0.25 | 0.5 ± 0.27 | 0.008 |
| Change of BCVA | −0.22 ± 0.27 | −0.24 ± 0.22 | −0.31 ± 0.32 | −0.19 ± 0.26 | −0.2 ± 0.26 | 0.007 |
| Within p-valueb | <0.001 | <0.001 | <0.001 | <0.001 | ||
| Pre-injection CMT | 447 ± 194 | 417 ± 129 | 452 ± 152 | 461 ± 158 | 471 ± 341 | 0.071 |
| Post-injection CMT | 277 ± 212 | 252 ± 41 | 294 ± 72 | 277 ± 386 | 279 ± 49 | 0.828 |
| Change (µm) CMT | −170 ± 284 | −138 ± 91 | −124 ± 67 | −182 ± 349 | −195 ± 338 | 0.445 |
| Within p-valueb | <0.001 | <0.001 | <0.001 | <0.001 | ||
IN inferonasal, IT inferotemporal, SN superonasal, ST superotemporal, BCVA best-corrected visual acuity, CMT central macular thickness
ap-Values are based on ANOVA
bp-Values are based on paired t-test