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. 2018 Sep 10;33(2):304–312. doi: 10.1038/s41433-018-0208-y

Table 2.

Comparison of pain, VA, and CMT values and their changes during the study follow-up among different injection sites

Total Injection site p-Valuea
IN IT SN ST
Pain 2.9 ± 2.2 3 ± 2.3 3 ± 2.1 1.5 ± 1.7 4 ± 2 <0.001
Pre-injection BCVA (logMAR) 0.64 ± 0.35 0.61 ± 0.37 0.65 ± 0.41 0.6 ± 0.31 0.69 ± 0.3 0.022
Post-injection BCVA (logMAR) 0.49 ± 0.26 0.42 ± 0.27 0.53 ± 0.24 0.48 ± 0.25 0.5 ± 0.27 0.008
Change of BCVA −0.22 ± 0.27 −0.24 ± 0.22 −0.31 ± 0.32 −0.19 ± 0.26 −0.2 ± 0.26 0.007
Within p-valueb <0.001 <0.001 <0.001 <0.001
Pre-injection CMT 447 ± 194 417 ± 129 452 ± 152 461 ± 158 471 ± 341 0.071
Post-injection CMT 277 ± 212 252 ± 41 294 ± 72 277 ± 386 279 ± 49 0.828
Change (µm) CMT −170 ± 284 −138 ± 91 −124 ± 67 −182 ± 349 −195 ± 338 0.445
Within p-valueb <0.001 <0.001 <0.001 <0.001

IN inferonasal, IT inferotemporal, SN superonasal, ST superotemporal, BCVA best-corrected visual acuity, CMT central macular thickness

ap-Values are based on ANOVA

bp-Values are based on paired t-test