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. 2019 Feb 7;9:1605. doi: 10.1038/s41598-019-38842-x

Figure 2.

Figure 2

MEDI-579 sequence. MEDI-579 is shown in alignment with parent sequence and closest human germline matches. CDR sequences are boxed. Vernier residues are marked in red above the sequence. Pink shading in MEDI-579 represents positions reverted to match closest germline. Yellow shading in MEDI-579 indicates positions mutated from parent during affinity maturation.