Table 2.
Optical coherence tomography angiography findings before and after intravitreal aflibercept treatment for diabetic macular edema.
| Pre-treatment | Post-treatment | P value | |
|---|---|---|---|
| BCVA before treatment | |||
| Landolt C acuity chart (mean; range) | 0.52 (0.15–1.0) | 0.71 (0.2–1.2) | |
| LogMAR (mean ± SD) | 0.28 ± 0.23 | 0.15 ± 0.22 | 0.003 |
| CRT (µm) (mean ± SD; range) | 484 ± 133 (313–828) | 275 ± 62 (190–458) | <0.001 |
| Microaneurysm, no. (%) | |||
| SCP | 4 (17) | 2 (9) | 0.665 |
| DCP | 20 (87) | 13 (57) | 0.049 |
| Retinal vascular area within 3 × 3 mm2 (%) | |||
| SCP (mean ± SD; range) | 3.82 ± 0.38 (2.84–4.46) | 3.82 ± 0.37 (2.98–4.46) | 0.994 |
| DCP (mean ± SD; range) | 3.88 ± 0.55 (2.46–4.66) | 3.90 ± 0.62 (2.07–4.75) | 0.842 |
| FAZ area within 3 × 3 mm2 (mm2) | |||
| SCP (mean ± SD; range) | 0.41 ± 0.20 (0.18–0.69) | 0.48 ± 0.24 (0.17–0.79) | 0.112 |
| DCP (mean ± SD; range) | 0.75 ± 0.34 (0.29–1.67) | 0.71 ± 0.33 (0.36–1.77) | 0.192 |
BCVA, best-corrected visual acuity; logMAR, logarithm of the minimum angle of resolution; CRT, central retinal thickness; SCP, superficial capillary plexus; DCP, deep capillary plexus; FAZ, foveal avascular zone; SD, standard deviation.