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. 2019 Feb 7;9:1561. doi: 10.1038/s41598-018-38248-1

Table 3.

Optical coherence tomography angiography parameters associated with post-treatment best-corrected visual acuity after intravitreal aflibercept.

Variable Univariate linear regression
Regression coefficient R2 P value
Age −0.0014 0.006 0.732
Sex (male: 0, female: 1) −0.179 0.138 0.081
NPDR or PDR (NPDR:0, PDR:1) 0.272 0.394 0.001
BCVA before treatment 0.625 0.452 <0.001
No. of injections 0.066 0.16 0.059
Retinal vascular area before treatment
 SCP −0.409 0.512 <0.001
 DCP −0.236 0.361 0.002
FAZ (mm2) before treatment
 SCP 0.187 0.029 0.438
 DCP 0.257 0.16 0.058
FAZ (mm2) after treatment
 SCP 0.266 0.084 0.179
 DCP 0.345 0.274 0.01
Retinal vascular area after treatment
 SCP −0.489 0.717 <0.001
 DCP −0.274 0.618 <0.001

BCVA, best-corrected visual acuity; logMAR, logarithm of the minimum angle of resolution; CRT, central retinal thickness; NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; SCP, superficial capillary plexus; DCP, deep capillary plexus; FAZ, foveal avascular zone; SD, standard deviation.