Table 4.
Drug | Model | Correlation | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Dose 1 | Dose 2 | Dose 3 | Dose 4 | Dose 5 | Dose 6 | Dose 7 | Dose 8 | Mean | ||
Erlotinib | MRF | 0.0293 | 0.2014 | 0.1877 | 0.2901 | 0.3915 | 0.4813 | 0.4942 | 0.4071 | 0.3103 |
FRF | 0.0662 | 0.1781 | 0.2138 | 0.3256 | 0.4378 | 0.4955 | 0.5094 | 0.4100 | 0.3296 | |
Nilotinib | MRF | −0.0725 | 0.1966 | 0.1550 | 0.2860 | 0.3734 | 0.4255 | 0.3888 | 0.1830 | 0.2420 |
FRF | −0.0776 | 0.1360 | 0.2186 | 0.3306 | 0.4182 | 0.4546 | 0.4310 | 0.2502 | 0.2702 | |
PD-0325901 | MRF | 0.1402 | 0.3722 | 0.4842 | 0.5395 | 0.5776 | 0.5871 | 0.5668 | 0.5181 | 0.4732 |
FRF | 0.2013 | 0.4397 | 0.5239 | 0.5798 | 0.6067 | 0.6078 | 0.5952 | 0.5426 | 0.5121 | |
PLX-4720 | MRF | −0.0522 | −0.0137 | 0.0885 | 0.1818 | 0.3986 | 0.4682 | 0.5018 | 0.3732 | 0.2433 |
FRF | −0.0045 | 0.1297 | 0.1259 | 0.2434 | 0.4028 | 0.4779 | 0.4973 | 0.3772 | 0.2812 | |
TAE-684 | MRF | 0.1068 | 0.1485 | 0.0045 | 0.1509 | 0.3236 | 0.3448 | 0.2914 | 0.2874 | 0.2072 |
FRF | 0.0978 | 0.1615 | 0.0541 | 0.2358 | 0.3654 | 0.3867 | 0.3736 | 0.3008 | 0.2470 |
All the models are built using 150 trees, m = 10 node splitting features and minimum leaf size of 10.