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. 2019 Feb 7;9:1614. doi: 10.1038/s41598-018-38214-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The representative images and bar chart analysis of the ex-vivo mouse aorta ring assay when treated with 12.5 µg/mL of NLC-Blank, NLC-Citral, and citral for 24 hours. The presence of the vessels protruding (Red arrow) from the aorta were counted. The experiment was done in triplicates and data are expressed as mean ± SD. Significance was set at p < 0.05 comparing between groups with (*) to NLC-Blank and (**) to citral.