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. 2019 Jan 1;16(2):212–220. doi: 10.7150/ijms.29930

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Overexpression of miR-29a in the murine model resulted in the downregulation of fibrosis in mice livers after BDL. (A) Histomorphometric analyses of alpha-smooth muscle actin (α-SMA) demonstrated strongα-SMA immunoreactivity (brown staining) in wild-type (WT) mice compared to those in miR-29aTg mice. (B) We measured the histomorphometric analyses of alpha-smooth muscle actin by independent color channel of an image J analysis. Data are expressed as the mean ± SE of six to eight samples per group. *indicates a p < 0.05 between the groups.