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. 2019 Jan 1;15(2):351–368. doi: 10.7150/ijbs.28522

Figure 3.

Figure 3

Ob- or HFD-exosomes impair activation of the insulin signaling pathway in vitro. (A) Effect of WT-, Ob- and HFD-exosomes on AKT phosphorylation of insulin-induced AML12 cells. TNF-α was used as a positive control and PBS was used as a negative control. *p <0.05, Ob-Exo vs WT-Exo, HFD-Exo vs WT-Exo. (B) Flow cytometry dot plots of 10000 AML12 cells. The 2D plots indicating the relative FL1 fluorescence intensity (2-NBDG) of AML12 cells. The Blank Control was AML12 cells without 2-NBDG, showed the spontaneous fluorescence intensity of AML12 cells. n=3 independent experiments. All values were expressed as means ± SD.