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. 2019 Jan 24;15(3):668–679. doi: 10.7150/ijbs.30168

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RA inhibits the in vivo growth of drug-resistant OS. (A) Macroscopic appearance of OS tumors in the tibia of BALB/c nude mice after treatment. Tumor weight quantification in BALB/c nude mice after treatment. (B) TUNEL assay of tumor samples from the leg in different treatment groups. (C) Body weight was measured every 3 days. (D) Tumor samples were lysed and subjected to immunoblotting with the indicated antibodies. β-actin was used as a loading control. *P<0.05, **P<0.01 compared with vehicle control.