Figure 1.
Expression of FBXO22 was down-regulated in RCC tissues and positive associated with overall and disease-free survival of RCC patients. (A) IHC assay of FBXO22 protein expression in normal Renal tissues and RCC tissues. Top panel, magnification, x100; Bottom panel, magnification, x200. (B) Quantification of the relative protein level of FBXO22 in normal Renal tissues and RCC tissues, the overall expression level of FBXO22 in the RCC tissues was significantly lower (P<0.01, χ2test). (C) High FBXO22 expression related to greater favorable overall cumulative survival of RCC patients (P = 0.001, log-rank test). (D) High FBXO22 expression related to greater favorable disease-free cumulative survival of RCC patients (P=0.003, log-rank test).