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Depletion of FBXO22 enhanced Angiogenesis in vitro. (A, B) Knockdown of FBXO22 promote HUVECs proliferation, as shown by CCK-8 assays. (C, D) Representative pictures were taken in situ for tube formation in the supernatant of 786-O and ACHN cells transfected with control siRNA (siCtrl) or small interfering RNAs (siRNAs) targeting FBXO22. Data are presented as the mean ± SD for three independent experiments, **P<0.01,***, P < 0.001.
