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. 2019 Jan 24;15(3):647–656. doi: 10.7150/ijbs.31293

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FBXO22 deprivation promoted RCC cell lung metastasis in vivo. (A) Stably carrying LLC-luc-shGFP and LLC-luc-shFBXO22 cells were injected into nude mice through tail vein. Bioluminescence images were shown. (B) The relative Firefly luciferase was shown in column diagram. Compared with the shCtrl group, the Firefly luciferase activity was increased following FBXO22 knockdown. (C) Statistical analysis of survival, the nude mice survival time was significantly shortened compared with the shCtrl group (n = 10 in each group). Data are presented as the mean ± SD, *P<0.05, **P<0.01.