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. 2019 Jan 1;15(3):579–586. doi: 10.7150/ijbs.29775

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Fig 5 — miR-9 could inhibit MCL-1 expression and MCL-1 knockdown was involved in miR-9-mediated Dnr sensitivity in AML cells. (A) Expression of MCL-1 protein in AML cells transfected with miR-9 mimics or negative control. ***P<0.001 vs control. (B) Expression of MCL-1 protein in AML cells transfected with a miR-9 inhibitor or negative control. ***P<0.001 vs control. (C) Effect of MCL-1 on the viability of AML cells transfected with MCL-1 siRNA or negative control under different concentrations of Dnr. (D) Interference of MCL-1 siRNA by western blotting. **P<0.01,***P<0.001 vs control. (E) Viability of AML cell lines transfected with MCL-1 siRNA plus a miR-9 inhibitor or CL-1 siRNA plus a negative control under different concentrations of Dnr according to the CCK-8 assay.