Table 5.
Case–control genetic association
| Gene | SNP ID | Chi-square statistic (χ2) | P-value |
|---|---|---|---|
| IL-10 | rs3024496 | 0.556 | 0.757 |
| IL-10 | rs1800872 | 1.120 | 0.571 |
| IL-10RA | rs3135932 | 0.464 | 0.863 |
| IL-10RB | rs2834167 | 2.867 | 0.238 |
| PD-1 | rs2227982 | 0.545 | 0.761 |
| PD-1 | rs10204525 | 1.221 | 0.543 |
| PD-L1 | rs4143815 | 0.638 | 0.727 |
| PD-L2 | rs7854413 | 5.012 | 0.082 |
CP = chronic pathology; EN = endemic normal; SNP = single-nucleotide polymorphism. Bold values represent the significant differences between EN individuals and CP patients for genotypes of PD-L2 SNP. Genotype differences in selected SNPs between EN individuals and patients with CP were tested using the χ2 test statistic.