3. Adverse effects on lamotrigine: number of participants experiencing each event.
Event | Frank 1999 | Coppola 2004 | Huang 2009 | Glauser 2013 |
Abdominal pain | 5 | |||
Headache | 2 | 2 | 14 | |
Nausea | 3 | 2* | ||
Vomiting | 2* | |||
Poor appetite | 2 | 9 | ||
Increased appetite | 1 | 10 | ||
Diarrhoea | 2 | |||
Dizziness | 3 | 5 | 5 | |
Hyperkinesia | 2 | |||
Hyperactivity | 12 | |||
Attention problems | 11 | |||
Hostility | 11 | |||
Concentration decreased | 9 | |||
Personality change | 10 | |||
Sleep problem | 5 | |||
Depression | 11 | |||
Slow process speed | 7 | |||
Memory problem | 8 | |||
Apathy | 3 | |||
Fatigue | 1 | 18 | ||
Rash | 10 | 1 | 2 | 6 |
Nervousness | 1 | |||
Diplopia | 1 |
* Nausea, vomiting, or both
Numbers of individuals within each study undertaking lamotrigine: 15 (Frank 1999), 19 (Coppola 2004), 24 (Huang 2009), 146 (Glauser 2013a).