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. 2019 Feb 8;2019(2):CD003032. doi: 10.1002/14651858.CD003032.pub4

Huang 2009.

Methods Randomised, parallel group unblinded study. Follow‐up 12 months.
Participants 48 drug‐naive participants, all with typical As, age 6 to 10 years
Interventions Monotherapy with VPS or LTG.
Outcomes Seizure freedom at 1, 3, 6 and 12 months.
Complete normalisation of EEG with seizure freedom.
Notes No information on sponsorship by pharmaceutical company was available.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to permit judgement.
Allocation concealment (selection bias) Unclear risk Insufficient information to permit judgement.
Blinding (performance bias and detection bias) 
 All outcomes High risk No blinding.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk No blinding.
Blinding of outcome assessment (detection bias) 
 All outcomes High risk No blinding.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing outcome data.
Selective reporting (reporting bias) Low risk The study protocol is not available but it is clear that the published reports include all expected outcomes.