Fig. 1.

The effects of h2E2 on urinary excretion of cocaine and metabolites. Mean ± S.E.M. excretion rates (in nanograms/6 hours) in vehicle-treated (black) and h2E2-treated (gray) animals for cocaine (A), BE (B), and EME (C) are shown. Asterisks represent statistical significance P < 0.05 from paired t tests comparing h2E2-treated to vehicle control–treated animals. All data were normalized to urine volumes to yield total excretion per 6-hour collection interval. Norcocaine was not detectable in any samples.