Table 3.
Drug | Formulation | Most relevant adverse events | Contraindications and warnings |
---|---|---|---|
Ivermectin | 3 and 6mg tablets | Encephalopathy in those with high levels (>20000/ml) of Loa loa microfilariae (mf) | Confirmed high levels of Loa loa mf < 15kg body weight Pregnancy Lactating women on 1st wk of puerperium |
Albendazole | 200 and 400mg tablets | Choking in infants | 1st trimester pregnancy Effective contraception is recommended during therapy and for 1 month after the last dose |
Thiabendazole | Tablets, 500 mg Suspension, 500 mg/5 mL |
Gastrointestinal: anorexia, nausea, vomiting, diarrhea, abdominal pain, jaundice, parenchymal liver damage. Central Nervous System: dizziness, weariness, drowsiness, headache, hyperirritability, seizures, tinnitus |
Activities requiring mental alertness should be avoided. |