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. Author manuscript; available in PMC: 2019 Jun 14.
Published in final edited form as: J Med Chem. 2018 May 24;61(11):4946–4960. doi: 10.1021/acs.jmedchem.8b00419

Figure 2.

Figure 2.

Key biosynthetic pathways involving (A) CYP17A1 and (B) CYP21A2 in human steroidogenesis. Progesterone is also a substrate for CYP17A1 17α-hydroxylation (not shown).