Table 3. . Associations between PGC1A and PGC1B CpG sites and cancer incidence.

Illumina ID	HR	95% CI	p-value	FDR	Gene	Region
cg15219393	3.71	1.82–7.58	<0.01	<0.01	PGC1B	First exon; 5′UTR
cg27514608	1.55	1.19–2.03	<0.01	0.02	PGC1A	TSS1500
cg09427718	0.46	0.20–0.79	0.01	0.07	PGC1A	Body
cg18604199	0.53	0.31–0.89	0.02	0.17	PGC1B	Body
cg10955995	0.58	0.34–1.00	0.05	0.34	PGC1A	Body
cg09814231	0.43	0.19–1.00	0.05	0.34	PGC1B	Body
cg16786458	0.60	0.35–1.02	0.06	0.35	PGC1B	TSS1500
cg25226657	0.59	0.32–1.09	0.09	0.48	PGC1B	Body
cg04893087	0.74	0.48–1.13	0.16	0.58	PGC1A	TSS1500
cg07744449	1.33	0.89–2.00	0.17	0.58	PGC1A	Body
cg20723350	0.77	0.53–1.12	0.17	0.58	PGC1A	First exon; 5′UTR
cg17645677	0.48	0.16–1.40	0.18	0.58	PGC1B	Body
cg11270806	1.21	0.91–1.62	0.19	0.58	PGC1A	TSS1500
cg27182172	0.61	0.28–1.30	0.20	0.58	PGC1A	Body
cg27461259	1.18	0.90–1.56	0.23	0.59	PGC1A	TSS1500
cg12691631	0.74	0.45–1.22	0.23	0.59	PGC1A	TSS200
cg06772578	0.75	0.47–1.22	0.25	0.59	PGC1A	3′UTR
cg21184132	0.74	0.40–1.40	0.36	0.81	PGC1B	TSS1500
cg15541091	1.23	0.76–1.98	0.40	0.82	PGC1A	Body
cg05158538	0.81	0.49–1.35	0.42	0.82	PGC1A	Body
cg20563759	0.83	0.52–1.32	0.42	0.82	PGC1B	TSS1500
cg26876242	0.81	0.47–1.39	0.44	0.82	PGC1B	Body
cg20534662	0.82	0.48–1.40	0.47	0.82	PGC1B	Body
cg08550435	1.19	0.71–1.97	0.51	0.82	PGC1A	Body
cg04681472	0.84	0.49–1.44	0.53	0.82	PGC1B	3′UTR
cg24716152	0.83	0.46–1.50	0.54	0.82	PGC1A	Body
cg18547262	1.19	0.66–2.14	0.56	0.82	PGC1B	TSS200
cg15049370	1.18	0.68–2.06	0.56	0.82	PGC1B	Body
cg02896941	0.91	0.64–1.30	0.61	0.82	PGC1A	Body
cg00966557	1.19	0.58–2.44	0.63	0.82	PGC1B	Body
cg07226964	0.88	0.51–1.51	0.63	0.82	PGC1B	Body
cg08928958	0.76	0.23–2.49	0.65	0.82	PGC1B	Body
cg19701879	0.93	0.67–1.29	0.66	0.82	PGC1A	Body
cg15809858	0.87	0.42–1.79	0.70	0.85	PGC1B	Body
cg23459643	0.93	0.59–1.48	0.77	0.90	PGC1B	TSS1500
cg16344026	0.93	0.47–1.84	0.84	0.93	PGC1B	First exon
cg09082664	1.06	0.54–2.09	0.86	0.93	PGC1A	Body
cg06051582	0.96	0.52–1.74	0.88	0.93	PGC1B	Body
cg10500461	0.94	0.41–2.15	0.89	0.93	PGC1B	Body
cg22236469	0.96	0.43–2.11	0.91	0.94	PGC1B	Body
cg13593479	1.01	0.54–1.89	0.98	0.98	PGC1B	Body