Table 2.
Selected demographics for MD STARnet case classifications and phenotype assignments
| All Cases |
No phenotype assigned |
DMD |
BMD |
P* | |||||
|---|---|---|---|---|---|---|---|---|---|
| Total | N | % | N | % | N | % | N | % | |
| 987 | 100% | 28 | 100% | 838 | 100% | 121 | 100% | ||
| State | 0.40 | ||||||||
| Arizona | 229 | 23% | 6 | 22% | 199 | 24% | 24 | 20% | |
| Colorado | 214 | 22% | 7 | 25% | 184 | 22% | 23 | 19% | |
| Georgia | 272 | 28% | 3 | 11% | 233 | 28% | 36 | 30% | |
| Hawaii | 23 | 3% | - | – | 22 | 3% | 1 | 1% | |
| Iowa | 124 | 12% | 3 | 11% | 104 | 12% | 17 | 14% | |
| New York | 125 | 12% | 9 | 32% | 96 | 12% | 20 | 17% | |
| Race/Ethnicity | 0.02 | ||||||||
| Non-Hispanic White | 576 | 58% | 18 | 64% | 482 | 58% | 76 | 635 | |
| Hispanic, Any Race | 200 | 20% | 4 | 14% | 182 | 22% | 14† | 12% | |
| Non-Hispanic Black | 68 | 8% | 3 | 10% | 57 | 7% | 8 | 7% | |
| Other | 61 | 6% | 1 | 4% | 54 | 6% | 6 | 5% | |
| Unknown | 82 | 8% | 2 | 8% | 63 | 8% | 17† | 14% | |
| MD STARnet Classification | 0.01 | ||||||||
| Definite | 820 | 83% | 26 | 93% | 693 | 83% | 101 | 83% | |
| Probable | 65 | 7% | 2 | 7% | 57 | 7% | 6 | 5% | |
| Possible | 94 | 10% | - | – | 84 | 10% | 10 | 8% | |
| Asymptomatic | 8 | 1% | - | – | 4 | 0% | 4† | 3% | |
| Level of Certainty | 0.01 | ||||||||
| High (3 variables) | 248 | 25% | - | – | 232 | 28% | 16 | 13% | |
| Med (2 variables) | 446 | 45% | - | – | 402 | 48% | 44 | 37% | |
| Low (1 variable) | 265 | 27% | - | – | 204 | 24% | 61† | 50% | |
| Molecular Index Variable | |||||||||
| DMD | 589 | 60% | 18 | 65% | 549 | 66% | 22 | 18% | 0.00 |
| BMD | 134 | 13% | 8 | 28% | 55 | 7% | 71† | 59% | |
| Inconclusive | 1 | 0% | - | – | 1 | 0% | 0 | 0% | |
| Missing | 263 | 27% | - | – | - | – | - | – | |
| Mobility Index Variable | |||||||||
| DMD | 525 | 53% | 1 | 0% | 524 | 63% | 01 | 0% | 0.37 |
| BMD | 90 | 9% | 18 | 64% | 1 | 0% | 71 | 59% | |
| Inconclusive | 327 | 33% | 8 | 29% | 277 | 33% | 42 | 35% | |
| Missing | 45 | 5% | - | – | - | – | - | ||
| Onset Index Variable | |||||||||
| DMD | 627 | 63% | 22 | 79% | 588 | 70% | 17† | 14% | 0.00 |
| BMD | 41 | 4% | 1 | 3% | 4† | 0% | 36† | 30% | |
| Inconclusive | 254 | 26% | 5 | 18% | 204 | 24% | 45 | 37% | |
| Missing | 65 | 7% | - | – | - | – | - | – | |
MD STARnet: Muscular Dystrophy Surveillance Tracking and Research Network; BMD: Becker muscular dystrophy; DMD: Duchenne muscular dystrophy.
*
Only predictive and non-predictive for BMD vs DMD were included in chi-square analyses. Non-predictive included wrong phenotype and inconclusive.
†
Cells contributing to chi-square differences with a standardized residual ≥|2.0|