Figure 4. . HSD1169 is a selective kinase inhibitor.

HSD1169 has a strong affinity for FLT3, JAK2 and 3 and MKNK2 (with a percent inhibition greater than 90% at 500 nM of HSD1169) but not other over 90 tested kinases (DiscoverX ScanEdge kinases, which are distributed across the kinome).