Table 1.
The correlation between p53 mutational status and clinicopathologic features in 78 NSCLC patients
| Clinicopathological feature | p53 | χ 2 | P-value | |
|---|---|---|---|---|
| WT (n = 35) | Mut (n = 43) | |||
| Gender | 1.4110 | 0.2349 | ||
| Male | 19 | 29 | ||
| Female | 16 | 14 | ||
| Age (years) | 0.2276 | 0.6333 | ||
| < 60 | 12 | 17 | ||
| ≥60 | 23 | 26 | ||
| Histological type | 4.2338 | 0.1165 | ||
| SCC | 8 | 17 | ||
| ADC | 27 | 26 | ||
| Differentiation | 3.8980 | 0.1424 | ||
| well | 5 | 4 | ||
| Moderate | 24 | 23 | ||
| poor | 6 | 16 | ||
| Nodes metastasis | 4.9079 | 0.0267* | ||
| N0 | 25 | 20 | ||
| N1-3 | 10 | 23 | ||
| Distant metastasis | – | 0.1232 | ||
| M0 | 35 | 39 | ||
| M1 | 0 | 4 | ||
| TNM stage | 6.4440 | 0.0399* | ||
| I | 16 | 15 | ||
| II | 7 | 12 | ||
| III-IV | 12 | 16 | ||
P by χ 2 test, squamous cell carcinoma (SCC), adenocarcinoma (ADC)
*P < 0.05 was considered significant