7. Methodological differences with published reviews on care delivered by nurses compared to doctors in primary care.

Focus of other reviews	Differences from our review
	Does not include meta‐analyses	Includes nurses working as supplements according to our definition	Includes non‐randomised studies	Focusses on particular countries	Has a particular focus on cost outcomes
Bonsall 2008 This literature review assesses the impact of advanced primary care nursing roles, particularly first contact nursing roles, for patients, nurses themselves, and their colleagues.	x	x	x
Hollinghurst 2006 This study used the literature search Horrocks 2002 and aims to estimate resource use for a typical same‐day primary care consultation and the cost difference of employing an extra salaried GP or nurse practitioner.	x			UK	x
Horrocks 2002 This systematic review compares effects of nurse practitioners and doctors providing care at first point on patient satisfaction, health status, process measures, and quality of care.		x	x	Developed countries
Martínez‐González 2014a; Martínez‐González 2014b; Martínez‐González 2015a; Martínez‐González 2015b; Martínez‐González 2015c Several systematic reviews investigating effects of nurses working as substitutes for doctors in primary care on clinical effectiveness, course of disease, process care, resource utilisation, and costs.		x
Martin‐Misener 2015 This systematic review determines the cost‐effectiveness of nurse practitioners delivering primary and specialised ambulatory care.		x			x
Naylor 2010 This structured literature review investigates the value of advance practice nurses in delivering primary care, with a particular emphasis on the contributions of nurse practitioners.	x	x	x
Newhouse 2011 This systematic reviews compares patient outcomes of care by advanced practice registered nurses (APRNs) to care by other providers (doctors or teams without APRNs).	x	x	x	USA
Swan 2015 This systematic review includes 10 studies evaluating the cost and quality of care provided by APRNs in primary care.	x

APRN: advanced practice registered nurse.