Table 2.
Architectural pattern and cytomorphological features observed on fine-needle aspiration cytology of gallbladder carcinoma
| Cytological features | Number of cases (%) |
|---|---|
| Architectural pattern | |
| Papillae | 22 (7.1) |
| Acini | 220 (71.6) |
| Sheets | 235 (76.5) |
| Rosettes | 5 (1.6) |
| Nuclear molding | 5 (1.6) |
| Cellular morphology | |
| Columnar cells | 120 (39) |
| Signet ring cells | 3 (0.9) |
| Squamous cells | 19 (6.1) |
| Small cells | 5 (1.6) |
| Clear cells | 2 (0.6) |
| Spindle cells | 1 (0.3) |
| Giant cells | 1 (0.3) |
| Intracellular mucin | 19 (6.1) |
| Nuclear pleomorphism | |
| Mild | 59 (19.2) |
| Moderate | 147 (47.8) |
| Severe | 101 (32.8) |
| Nuclear chromatin | |
| Fine chromatin | 20 (6.5) |
| Vesicular chromatin | 182 (59.2) |
| Coarse chromatin | 100 (32.5) |
| Salt and pepper chromatin | 5 (1.6) |
| Mitotic figures | |
| <5/high-power field | 74 (24.1) |
| 5-10/high-power field | 144 (46.9) |
| >10/high-power field | 89 (28.9) |
| Background | |
| Necrosis | 192 (62.5) |
| Mucin | 22 (7.1) |
| Inflammatory | 139 (45.2) |
| Keratinous material | 17 (5.5) |