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. 2019 Feb 1;10:133. doi: 10.3389/fimmu.2019.00133

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Copyright © 2019 Fadeel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Receptor recognition of nanoparticles. Proposed model of the interaction between the scavenger receptor, SR-AI, a so-called pattern recognition receptor, and crystalline magnetite. (A) 2D frontal and rotated projections of the magnetite unit cell. (B) 3D view of the crystal unit approaching the charged collagen-like domain of SR-A1. Reprinted with permission from Chao et al. (28). Copyright (2013) American Chemical Society.