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. 2019 Feb 5;11:117–128. doi: 10.2147/CEOR.S183076

Table 4.

Long-term analyses: costs

Treatment sequence Time horizon (years) Sarilumab costs (US$) Adalimumab costs (US$) Incremental total costs: sarilumab vs adalimumab
Drug Routine Total Drug Routine Total
Next line: csDMARD palliative treatment 1 $33,056 $4,039 $37,095 $47,378 $4,150 $51,527 −$14,432
5 $95,039 $19,278 $114,317 $122,202 $19,837 $142,039 −$27,722
10 $140,728 $36,248 $176,977 $175,063 $37,073 $212,136 −$35,159
Next lines: tofacitinib > csDMARD palliative treatment 5 $133,457 $18,850 $152,307 $163,474 $19,370 $182,844 −$30,537
10 $195,620 $35,776 $231,396 $232,544 $36,568 $269,112 −$37,716
Next lines: etanercept > csDMARD palliative treatment 5 $165,186 $18,384 $183,570 $198,083 $18,849 $216,931 −$33,362
10 $247,966 $34,880 $282,847 $288,019 $35,603 $323,621 −$40,774
Next lines: etanercept > tofacitinib > csDMARD palliative treatment 5 $188,847 $18,122 $206,969 $223,368 $18,578 $241,946 −$34,977
10 $288,454 $34,471 $322,925 $330,455 $35,186 $365,640 −$42,716

Abbreviation: csDMARD, conventional synthetic disease-modifying antirheumatic drug.