Table 1.
Datasets of ZHX family members in breast cancer (Oncomine database)
| Gene | Dataset | Normal (cases) | Tumor (cases) | Fold change | t-test | P-value |
|---|---|---|---|---|---|---|
| ZHX1 | Ma 4 | Breast (14) | Ductal breast carcinoma in situ (9) | 1.347 | 2.150 | 0.027 |
| Curtis | Breast (144) | Invasive breast carcinoma (21) | 1.064 | 2.209 | 0.018 | |
| Breast (144) | Invasive breast carcinoma (1,556) | 1.026 | 2.247 | 0.013 | ||
| Breast (144) | Tubular breast carcinoma (67) | 1.062 | 3.372 | 4.73E-4 | ||
| ZHX2 | TCGA | Breast (61) | Invasive lobular breast carcinoma (36) | 1.202 | 3.114 | 0.001 |
| Breast (61) | Invasive ductal breast carcinoma (389) | 1.117 | 2.820 | 0.003 | ||
| Breast (61) | Invasive breast carcinoma (76) | 1.136 | 2.351 | 0.010 | ||
| Breast (61) | Mixed lobular and ductal breast carcinoma | 1.510 | 2.613 | 0.019 | ||
| ZHX3 | Ma 4 | Breast (14) | Invasive breast carcinoma in situ (9) | 1.337 | 2.000 | 0.035 |
| TCGA | Breast (61) | Invasive ductal breast carcinoma (389) | 1.317 | 4.649 | 6.83E-6 | |
| Breast (61) | Invasive breast carcinoma (76) | 1.256 | 3.392 | 4.83E-4 | ||
| Breast (61) | Invasive ductal and lobular carcinoma (3) | 1.389 | 6.499 | 0.009 |
Abbreviation: TCGA, The Cancer Genome Atlas.