Table 2.

The inclusion and exclusion criteria of LI-RADS (CT, MRI, CEUS, and ultrasound surveillance)

Surveillance ultrasound target population

• Inclusion:

◦ Adults with cirrhosis of any cause

◦ Subsets of adult patients with chronic HBV infection, even in the absence of cirrhosis

◦ Asian male hepatitis B carriers over age 40 years

◦ Asian female hepatitis B carriers over age 50 years

◦ Hepatitis B carrier with family history of HCC

◦ African or North American blacks with hepatitis B

• Exclusion:

◦ Child–Pugh C cirrhosis, unless patient is a transplant candidate

• Population in which benefit of surveillance is uncertain:

◦ Adults with NASH but without cirrhosis

◦ Adults with chronic hepatitis C without cirrhosis

Diagnostic population for LI-RADS (CT, MRI, and CEUS)

• Inclusion:

◦ Adults with cirrhosis

◦ Chronic hepatitis B

◦ Current or prior HCC including adult liver transplantation candidates and patients posttransplant

• Exclusion:

◦ Cirrhosis due to vascular disorder or congenital hepatic fibrosis

◦ Pediatric patients

Notes: Target populations for screening and surveillance and target population for diagnostic imaging with CT, MRI, or CEUS. Guidelines based on the American Association for Study of Liver Diseases (AASLD).¹

Abbreviations: CEUS, contrast-enhanced ultrasound; HCC, hepatocellular carcinoma; HPV, hepatitis B virus; LI-RADS, Liver Imaging Reporting and Data System; NASH, nonalcoholic steatohepatitis.