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. 2019 Feb 5;14:977–991. doi: 10.2147/IJN.S190766

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© 2019 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Adhesion, proliferation, migration, and osteogenic differentiation of BMSCs in conditioned medium.

Notes: (A) Adhesion of BMSCs on different Ti surfaces; (B) migration of BMSCs on Ti surfaces in Transwell: greater BMSC migration was observed on the ASA-loaded Ti surface than on the blank surface; (C) effects of the conditioned medium of RAW264.7 cells on osteogenic-related gene expression of BMSCs after culturing for 7 and 14 days, as detected by qPCR: (a) COL I gene, (b) OCN gene, (c) ALP gene, and (d) RUNX2 gene. *P<0.05, n=3.

Abbreviations: ASA, aspirin; BMSCs, bone marrow stromal cells; COL I, type I collagen; OCN, osteocalcin; qPCR, quantitative PCR; RUNX2, runt-related transcription factor 2; Ti, titanium.