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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: J Am Board Fam Med. 2018 Jul-Aug;31(4):503–513. doi: 10.3122/jabfm.2018.04.180008

Table 2.

Age-standardized prevalence of 2 or more multi-morbidities for participants aged 20 years or older stratified by age, sex, race, poverty, education, and insurance status for NHANES 1988–2014.

1988–1994 (n=16573) 1999–2000 (n=4222) 2001–2002 (n=4792) 2003–2004 (n=4742) 2005–2006 (n=4481) 2007–2008 (n=5660) 2009–2010 (n=6011) 2011–2012 (n=5281) 2013–2014 (n=5541) P for trend
No. with 2 or more multi-morbidities* 8535 2528 2735 2900 2664 3519 3618 3135 3354
Overall prevalence (%)± 45.7 (43.5–47.8) 51.9 (48.0–55.8) 51.2 (48.3–54.0) 55.8 (52.7–58.9 57.0 (54.0–60.0) 56.8 (53.5–60.1) 55.2 (52.9–57.4) 57.4 (54.0–60.8) 59.6 (58.1–61.1) <.0001
Age group, y
 20–44 26.6 (24.2–28.9) 30.9 (26.9–34.9) 31.9 (29.3–34.6) 34.5 (31.5–37.5) 35.4 (30.9–39.9) 35.1 (31.3–39.0) 32.4 (30.2–34.6) 34.9 (31.4–38.4) 37.5 (35.4–39.5) <.0001
 45–64 63.1 (61.0–65.3) 68.0 (61.5–74.5) 63.6 (59.4–67.7) 70.1 (66.2–73.9) 69.0 (66.3–71.7) 68.8 (65.2–72.3) 67.3 (64.4–70.2) 69.2 (66.5–72.0) 70.6 (67.5–73.6) <.0001
 65+ 83.5 (81.5–85.6) 91.7 (89.8–93.6) 88.9 (86.6–91.1) 90.6 (88.6–92.6) 91.5 (89.2–93.8) 90.5 (88.4–92.5) 90.8 (89.3–92.4) 89.8 (87.5–92.0) 91.8 (88.6–95.1) <.0001
Sex
 Male 45.6 (43.6–47.5) 51.3 (46.0–56.8) 51.3 (48.6–54.0) 54.6 (51.4–57.9) 54.8 (51.8–57.8) 54.4 (51.2–57.5) 54.8 (52.7–56.9) 54.5 (52.0–57.0) 56.1 (54.8–57.3) <.0001
 Female 50.2 (48.5–51.9) 54.9 (51.2–58.5) 52.3 (49.8–54.7) 56.2 (53.4–59.0) 56.7 (53.7–59.6) 56.4 (53.1–59.7) 52.4 (50.7–54.1) 56.1 (53.4–58.7 58.7 (56.9–60.5) <.0001
Race
 Hispanic 46.9 (45.2–48.7) 49.6 (45.3–53.9) 48.0 (43.6–52.3) 50.5 (46.3–54.6) 49.8 (46.5–53.1) 51.5 (48.5–54.4) 51.1 (47.5–54.7) 56.2 (52.4–60.0) 54.9 (52.8–57.1) <.0001
 White 44.0 (38.7–49.4) 53.5 (49.0–57.9) 52.2 (49.6–54.7) 56.6 (53.9–59.3) 56.5 (53.4–59.6) 56.3 (51.8–60.8) 53.9 (51.9–55.9) 55.1 (51.7–58.5) 59.2 (57.5–60.9) <.0001
 Black 47.9 (45.9–49.9) 57.5 (55.4–59.5) 56.0 (54.2–57.9) 58.8 (56.5–61.1) 58.9 (55.5–62.3) 58.6 (55.5–61.7) 61.5 (58.7–64.5) 61.6 (59.0–64.2) 60.1 (56.7–63.4) <.0001
 Others 52.9 (51.3–54.5) 52.7 (37.7–67.7) 47.9 (40.7–55.0) 45.3 (34.5–56.1) 53.5 (44.8–62.3) 49.8 (40.3–59.2) 42.6 (37.6–47.6) 45.0 (41.2–48.9) 45.0 (42.0–48.0) .11
Ratio of family income to poverty
 Above
 Poverty
 (≥1.0)
47.4 (45.7–49.2) 52.7 (48.9–56.5) 51.4 (49.0–53.9) 55.3 (52.5–58.0) 55.6 (52.5–58.7) 55.3 (52.8–57.9) 53.4 (51.9–55.0) 54.8 (52.5–57.2) 57.5 (56.1–58.9) <.0001
 Under
 Poverty
 (<1.0)
53.1 (50.5–55.8) 58.9 (52.4–65.4) 54.0 (48.7–59.3) 58.4 (52.9–64.0) 57.1 (52.2–61.9) 59.1 (53.4–64.8) 58.4 (55.2–61.7) 57.0 (53.0–61.0) 58.0 (54.5–61.6) .001
Health insurance
 Yes 48.1 (46.3–50.0) 54.2 (49.7–58.7) 52.9 (51.1–54.7) 57.0 (54.2–59.8) 57.5 (54.4–60.6) 56.6 (53.2–60.0) 54.6 (52.9–56.2) 55.5 (53.2–57.9) 58.7 (57.1–60.4) <.0001
 No 43.1 (38.3–47.8) 47.9 (40.7–55.1) 46.4 (38.5–54.3) 46.7 (40.0–53.3) 48.9 (44.9–53.0) 50.5 (46.4–54.7) 48.8 (44.1–53.4) 53.9 (50.0–57.7) 51.3 (47.7–54.9 <.0001
Education
 ≥ High
 school
46.4 (44.7–48.2) 52.9 (48.6–57.2) 51.4 (49.3–53.6) 54.9 (52.4–57.4) 55.8 (52.8–58.9) 54.8 (51.8–57.9) 53.2 (51.7–54.7) 54.4 (52.0–56.7) 57.4 (56.1–58.8) <.0001
 < High
 school
52.5 (50.0–55.0) 54.4 (49.9–58.9) 53.8 (49.8–57.9) 58.2 (53.4–63.1) 56.1 (53.0–59.3) 57.6 (52.7–62.5) 55.5 (51.4–59.5) 60.3 (56.1–64.4) 57.1 (53.1–61.0) .05
*

Unweighted total number of subjects with 2 or more multi-morbidities

±

Weighted overall prevalence of 2 or more multi-morbidities

p-value from logistic regression analysis.

Chronic conditions included in determining multi-morbidity: cardiovascular disease (CVD), chronic obstructive pulmonary disease (COPD), chronic kidney disease (CKD), asthma, arthritis, cancer, stroke, hypertension, hyperlipidemia, diabetes, and obesity.